Translocation Down syndrome can be passed from parent to child.
However, only about 3 to 4 percent of children with Down syndrome have translocation and only some of them inherited it from one of their parents.
This extra genetic material causes the developmental changes and physical features of Down syndrome.
Down syndrome varies in severity among individuals, causing lifelong intellectual disability and developmental delays.
Down syndrome is a disorder that is caused by an extra number 21 chromosome.
This affects one in every 800 births worldwide, and causes birth defects. Most research says that there have always been people suffering from Down syndrome.Another chromosomal irregularity is Mosaic Down syndrome.This is when only some cells in the body have the extra chromosome.There are other chromosomal irregularities that cause Down syndrome.The first one is call translocation which is when a piece of the 21st chromosome attaches itself to another chromosome.Dr Jon Langdon Down was the first person to recognize this.Down syndrome was also known as "mongolism" because the people who had it seemed to resemble Mongolian Asians.Most children with Down syndrome have mild to moderate cognitive impairment.Language is delayed, and both short and long-term memory is affected.This is a defect where a third copy of chromosome 21 is in every cell in the body of the person.The age of the mother is one of the reasons for Trisomy 21.